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MT 63-78 is a small-molecule research compound that functions as a direct activator of AMP-activated protein kinase (AMPK) and inhibits mTORC1 signaling. It induces mitotic arrest and apoptosis, and has reported antitumor effects, including blocking prostate cancer growth via suppression of lipogenesis and mTORC1 pathways.
Direct AMPK activator with reported EC50 25 μM
Induces mitotic arrest and apoptosis in cellular assays
Reported antitumor activity, including inhibition of prostate cancer growth
Molecular weight 326.35 g/mol; formula C21H14N2O2
Purity 98.0%
Available in 1 mg, 5 mg, 10 mg, 50 mg, 100 mg packs; store protected from light at 4°C (in solvent: -80°C for 6 months, -20°C for 1 month)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
2'-TOM MeC(Ac) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 25 g. Store at -20 °C. Ships on dry ice. SDS available for reference.
Specifications - CAS: 872548-65-7 - MDL: No data - InChIKey: OBHVHGNMPRNNPM-RNGKMJNNSA-N - Molecular Weight: 988.247761998 - Molecular Formula: C52H74N5O10PSi - Purity: ≥95% - Container Type: 125 mL HDPE - Pack Size: 25 g - Net Weight: 25 g - Gross Weight: 54.3 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@@H]1[C@H](O[C@@H](N2C=C(C(NC(C)=O)=NC2=O)C)[C@@H]1OCO[Si](C(C)C)(C(C)C)C(C)C)COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OCCC#N)C(C)C)C
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
BA-53038B is a hepatitis B virus (HBV) core protein allosteric modulator that binds the HAP pocket and modulates capsid assembly. It shows antiviral activity against HBV (EC50 = 3.32 μM) with low cytotoxicity (CC50 > 100 μM). Supplied as a solid research reagent with high reported purity and good solubility in DMSO.
Modulates HBV capsid assembly by binding the HAP pocket.